报告时间：12月28日上午10:00

报告地点：曲江校区西五楼A302会议室

报告题目：Nanomechanics and Biomechanics in Cell and Tissue Engineering 

报告人：Dr. Jinju (Vicky) Chen, Lecturer in Nano-Biomechanics,School of Mechanical & System Engineering,Newcastle University,   NE1 7RU,United Kingdom
E-mail: Jinju.chen@ncl.ac.uk

Cell mechanics and cell-materials interactions are important for disease diagnosis and tissue engineering. The synergistic combination of computational modelling and experimental approaches allows exploring phenomena in cell mechanics and mechanotransduction that are not easily accessible with experimental methods alone. A hybrid modelling–nanomechanical testing approach enables determining the viscoelastic properties of the living cells, which is useful to quantify the biomechanical effects of drug treatment, diseases and aging [1-2]. Such a nano-biomechanical technique can also be applied to assess the micro(nano)scale mechanical properties of engineered bone [3], extracellular matrix [4-5] and scaffold materials [6] which could further the understanding cell-materials interactions.  In addition, this presentation will cover how cells respond to two-dimensional and three-dimensional micromechanical environment [7-9], which will help a better understanding of the mechanotransduction and provide valuable guide for optimising  scaffold design and cell manipulations for desired tissue engineering.